CBD drug interactions

Medical
22 minute slide talk about cannabidiol potential interactions and clinical experience with a thousand patients. A focus on cytochrome interactions possible but uncommon in practice. At usual doses for depression of 30mg interactions is rare. At high doses (200mg) CBD relatively inhibit synaptic uptake noradrenaline, dopamine, serotonin, and GABA as well as liver degradation pathways: CYP3A4 and CYP2C19 , CYP2D6 enzymes, inhibition, degradation pathways. Recommendation: start with low dose (1/2 serving size) and increase slowly every other day.

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